Pediatric cancer treatment usually includes a combination of the following therapies:
- Chemotherapy
- Radiation
- Surgery
- Hematopoietic Stem Cell Transplant
- Biological Therapy
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If your patient does not have a Survivor Healthcare Plan (SHP), please refer him/her to the appropriate survivor clinic.
Intensity and duration of treatment can influence childhood cancer survivors' risk for late effects. It is important to have accurate treatment information to develop the risk profile and surveillance plan.
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The Children's Oncology Group Long-term Follow-up Guidelines identify late effects associated with specific cancer therapy. To utilize the guidelines the class of chemotherapy and field of radiation must be known.
These tables have been created to assist healthcare providers in identifying the categories of exposure used in the QuickFact tables.
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Chemotherapy Class
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Chemotherapy – Generic Name
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Chemotherapy – Brand Name/Index Term
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Alkylating Agents
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Carmustine
Busulfan
Chlorambucil
Cyclophosphamide
Ifosfamide
Lomustine
Melphalan
Procarbazine
Thiotepa
Mechlorethamine
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BCNU
Cytoxan
CCNU
Nitrogen Mustard, Mustargen
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Heavy Metals
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Cisplatin
Carboplatin
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CDDP, Platinol
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Antimetabolites
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Cytarabine
Mercaptopurine
Thioguanine
Methotrexate
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Cytosine Arabinoside, Ara-C
6MP, Purinethol
6TG
MTX
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Anthracycline antibiotics
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Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Mitoxantrone
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Adriamycin, ADR
Idamycin
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Anti-tumor antibiotics
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Bleomycin
Dactinomycin
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Actinomycin D, ACT
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Corticosteroids
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Dexamethasone
Prednisone
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Decadron
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Enzymes
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Asparaginase
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L-Asparaginase
Elspar
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Plant alkaloids
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Vincristine
Vinblastine
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Oncovin
Velban
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Epipodophyllo-toxins
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Etoposide
Etopophos
Teniposide
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VP16
VM26
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Radiation fields by anatomic region
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Radiation treatment fields
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Radiation treatment fields that include more than one anatomic region
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Head/Brain
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Cranial
Orbital/Eye
Ear/Infratemporal
Nasopharylgeal
Oropharyngeal
Waldeyer’s Ring
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Total Body Irradiation
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Neck
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Cervical (neck)
Supraclavicular
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Total Body Irradiation
Mini-Mantle
Mantle
Extended Mantle/Subtotal Lymphoid Irradiation
Total Lymphoid Irradiation
Spine
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Thorax
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Chest (thorax)
Whole Lung
Mediastinal
Axilla
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Total Body Irradiation
Mini-Mantle
Mantle
Extended Mantle/Subtotal Lymphoid Irradiation
Total Lymphoid Irradiation
Spine
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Abdomen
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Hepatic
Renal
Upper quadrant (right) (left)
Spleen (partial) (entire)
Paraaortic
Flank/Hemiabdomen (if field did not extend below iliac crest)
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Total Body Irradiation
Inverted Y /
Whole Abdomen
Extended Mantle/Subtotal Lymphoid Irradiation
Flank/Hemiabdomen (if field extended below iliac crest)
Total Lymphoid Irradiation
Spine
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Pelvis
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Pelvic
Vaginal
Prostate
Bladder
Iliac
Inguinal
Femoral
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Total Body Irradiation
Inverted Y /
Whole Abdomen
Extended Mantle/Subtotal Lymphoid Irradiation
Flank/Hemiabdomen (if field extended below iliac crest)
Total Lymphoid Irradiation
Spine
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Radiation treatment fields that
include more than one anatomic
region
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Anatomic region(s) included in field
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Mini-Mantle
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Neck
Axilla
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Mantle
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Neck
Thorax
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Extended Mantle/
Subtotal Lympoid Irradiation
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Neck
Thorax
Abdomen
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Inverted Y/Whole Abdomen
Flank/Hemiabdomen
(if field extended below iliac crest)
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Abdomen
Pelvis
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Total Lymphoid Irradiation
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Neck
Axilla
Thorax
Abdomen
Pelvis
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Spine
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Neck
Thorax
Abdomen
Pelvis
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Total Body Irradiation
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Head/Brain
Neck
Thorax
Abdomen
Pelvis
Testicular
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